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Brain Res. 1990 Oct 15;530(1):117-20.

Delayed wallerian degeneration in sciatic nerves of C57BL/Ola mice is associated with impaired regeneration of sensory axons.

Author information

1
Department of Physiology, Queen's University, Kingston, Ontario, Canada.

Abstract

Wallerian degeneration is delayed following sciatic nerve crush in C57BL/Ola mice. Compared to C57BL/6J mice, regeneration of sensory axons is significantly slowed in the Ola mice, but reinnervation does eventually occur. We conclude that Wallerian degeneration is a prerequisite for normal sensory axon regeneration following a crush injury to peripheral nerve.

PMID:
2271939
DOI:
10.1016/0006-8993(90)90666-y
[Indexed for MEDLINE]

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