Format

Send to

Choose Destination
See comment in PubMed Commons below
Tex Heart Inst J. 2012;39(3):420-3.

Multiple instances of peripheral artery emboli from occult primary small cell lung cancer.

Author information

1
Department of Vascular & Endovascular Surgery, Policlinico Casilino in Rome, 00169 Rome, Italy. rogadoc@libero.it

Abstract

Most peripheral artery emboli originate in the heart, and systemic neoplastic emboli are infrequently associated with bronchogenic carcinoma. To our knowledge, there have been no reports of pulmonary vein infiltration by small cell lung cancer.We describe a highly unusual case of multiple instances of peripheral embolism as the first overt sign of occult primary small cell lung cancer. Tumor emboli infiltrated the pulmonary veins of a 62-year-old man who presented first with a transient ischemic attack and then with other ischemic symptoms. The uncommonly wide distribution of tumor emboli over a short time resulted in death.Improvements in diagnostic imaging have led to the early identification of relatively isolated small cell lung cancers. This patient's case underscores the importance of transesophageal echocardiography in detecting cardiac emboli when the cause of cerebral ischemic attack is unknown or if there might be multiple instances of arterial embolism. Computed tomography also has a role in the investigation of possible sources of emboli and unrecognized, asymptomatic embolization.

KEYWORDS:

Carcinoma, bronchogenic/complications/pathology; carcinoma, small cell; embolism/complications/diagnosis/pathology; ischemic attack, transient/etiology; lung neoplasms/complications; neoplasm invasiveness; neoplastic cells, circulating; pulmonary veins/pathology/ultrasonography

PMID:
22719159
PMCID:
PMC3368466
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center