Format

Send to

Choose Destination
Microbes Infect. 2012 Oct;14(12):1009-16. doi: 10.1016/j.micinf.2012.06.003. Epub 2012 Jun 17.

Animal models to study the pathogenesis of enterotoxigenic Clostridium perfringens infections.

Author information

1
California Animal Health and Food Safety Laboratory System, San Bernardino Branch, School of Veterinary Medicine, University of California, Davis, San Bernardino, CA 92408, USA. fuzal@cahfs.ucdavis.edu

Abstract

Rabbits, mice, rats, non-human primates, sheep and cattle have been used to study the effect of Clostridium perfringens enterotoxin (CPE). CPE produces mostly necrosis of the small intestinal epithelium along with fluid accumulation in rabbits and mice. In the latter, CPE can bind to internal organs such as the liver, which induces lethal potassium levels in blood.

PMID:
22713745
PMCID:
PMC3572749
DOI:
10.1016/j.micinf.2012.06.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center