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BMJ Case Rep. 2011 Feb 24;2011. pii: bcr0920103377. doi: 10.1136/bcr.09.2010.3377.

Human papilloma virus: differentiating new primary lung cancer versus metastatic disease from previous head and neck squamous cell carcinoma.

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1
Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada.

Abstract

Distinguishing new primary lung tumours from lung metastasis in patients with head and neck squamous cell carcinoma (SCC) is a challenging clinical problem. Histological examination is not always able to distinguish between these scenarios as SCC is common in both sites. Here the authors present a case of metachronous cancers of the head and neck and lung in which human papilloma virus testing was proposed as a mechanism to distinguish primary from metastatic carcinoma.

PMID:
22707575
PMCID:
PMC3062858
DOI:
10.1136/bcr.09.2010.3377
[Indexed for MEDLINE]
Free PMC Article
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