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Cell Stem Cell. 2012 Jun 14;10(6):650-652. doi: 10.1016/j.stem.2012.05.004.

Mobilizing endogenous stem cells for repair and regeneration: are we there yet?

Author information

1
Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto M5G 1L7, Canada; McEwen Center for Regenerative Medicine, University of Toronto, Toronto M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto M5G 1X5, Canada; Department of Physiology, University of Toronto, Toronto M5G 1X5, Canada. Electronic address: fredam@sickkids.ca.
2
Cell Biology Program, Hospital for Sick Children, Toronto M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto M5G 1X5, Canada.

Abstract

Harnessing endogenous repair mechanisms to promote tissue regeneration in situations in which it does not normally occur has long been a goal in biomedical science. Recent advances in tissue stem cells indicate that this goal may now be achievable. Here we consider both the promise and the hurdles we still have to overcome.

PMID:
22704501
DOI:
10.1016/j.stem.2012.05.004
[Indexed for MEDLINE]
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