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Eksp Klin Farmakol. 2012;75(4):10-2.

[Effect of phenibut and its composition with nicotinic acid on hemostasis in rats with brain ischemia].

[Article in Russian]


It is shown that, in rats with global cerebral ischemia modeled by a complete irreversible occlusion of the common carotid artery and forced hypotension, the hemostasis is characterized by a shift toward hypercoagulation. A single preventive introduction of phenibut and, to a greater degree, a composition of phenibut with nicotinic acid, in rats with acute cerebral ischemia reduced the extent of disturbances in the hemostasis system of experimental animals.

[Indexed for MEDLINE]

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