Operative hysteroscopy intravascular absorption syndrome: A bolt from the blue

Indian J Anaesth. 2012 Mar;56(2):179-82. doi: 10.4103/0019-5049.96342.

Abstract

Operative hysteroscopy has emerged as an effective alternative to hysterectomy and has become standard surgical treatment for varied gynaecological conditions like abnormal uterine bleeding and uterine myomas. This procedure requires distention of the uterine cavity for adequate visualization of the operative field. 1.5% glycine is a widely used distention medium because it has good optical properties and is non-conductive. However, the intraoperative absorption of this electrolyte-free fluid can cause hyponatraemia, hypoosmolality, hyperglycinaemia and volume overload, including pulmonary oedema. We report a case of operative hysteroscopy intravascular absorption (OHIA) syndrome, presenting abruptly during hysteroscopic myomectomy, employing 1.5% glycine as the fluid distention medium. Successful management of the case and prevention strategies are discussed.

Keywords: Dilutional hyponatraemia; glycine fluid overload; operative hysteroscopy intravascular absorption syndrome; transurethral resection of prostate syndrome.