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Intern Med J. 2012 Jun;42(6):719-21. doi: 10.1111/j.1445-5994.2012.02809.x.

Point-prevalence study of inappropriate antibiotic use at a tertiary Australian hospital.

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Department of Infectious Diseases and Microbiology, Royal Perth Hospital, Perth, WA 6000, Australia.


A point-prevalence study at a tertiary Australian hospital found 199 of 462 inpatients (43%) to be receiving antibiotic therapy. Forty-seven per cent of antibiotic use was discordant with guidelines or microbiological results and hence considered inappropriate. Risk factors for inappropriate antibiotic prescribing included bone/joint infections, the absence of infection, creatinine level >120 µmol/L, carbapenem or macrolide use and being under the care of the aged care/rehabilitation team. In the setting of finite antimicrobial stewardship resources, identification of local determinants for inappropriate antibiotic use may enable more targeted interventions.

[Indexed for MEDLINE]

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