Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performance

Int J Sport Nutr Exerc Metab. 2012 Jun;22(3):175-83. doi: 10.1123/ijsnem.22.3.175.

Abstract

Purpose: To determine the effects of ingesting caffeine (CAFF) and sodium bicarbonate (SB), taken individually and simultaneously, on 3-km cycling time-trial (TT) performance.

Method: Ten well-trained cyclists, age 24.2 ± 5.4 yr, participated in this acute-treatment, double-blind, crossover study that involved four 3-km cycling TTs performed on separate days. Before each TT, participants ingested either 3 mg/kg body mass (BM) of CAFF, 0.3 g · kg⁻¹ · BM⁻¹ of SB, a combination of the two (CAFF+SB), or a placebo (PLAC). They completed each 3-km TT on a laboratory-based cycle ergometer, during which physiological, perceptual, and performance measurements were determined. For statistical analysis, the minimal worthwhile difference was considered ~1% based on previous research.

Results: Pretrial pH and HCO₃ were higher in SB and CAFF+SB than in the CAFF and PLAC trials. Differences across treatments for perceived exertion and gastric discomfort were mostly unclear. Compared with PLAC, mean power output during the 3-km TT was higher in CAFF, SB, and CAFF+SB trials (2.4%, 2.6%, 2.7% respectively), resulting in faster performance times (-0.9, -1.2, -1.2% respectively). Effect sizes for all trials were small (0.21-0.24).

Conclusions: When ingested individually, both CAFF and SB enhance high-intensity cycling TT performance in trained cyclists. However, the ergogenic effect of these 2 popular supplements was not additive, bringing into question the efficacy of coingesting the 2 supplements before short-duration high-intensity exercise. In this study there were no negative effects of combining CAFF and SB, 2 relatively inexpensive and safe supplements.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Athletic Performance / physiology*
  • Bicarbonates / blood
  • Bicycling / physiology*
  • Caffeine / pharmacology*
  • Central Nervous System Stimulants / pharmacology*
  • Cross-Over Studies
  • Double-Blind Method
  • Drug Therapy, Combination
  • Exercise Test
  • Humans
  • Hydrogen-Ion Concentration
  • Male
  • Physical Exertion / physiology*
  • Sodium Bicarbonate / blood
  • Sodium Bicarbonate / pharmacology*
  • Stomach Diseases / etiology
  • Young Adult

Substances

  • Bicarbonates
  • Central Nervous System Stimulants
  • Caffeine
  • Sodium Bicarbonate