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Chimerism. 2012 Jan-Mar;3(1):1-8.

Immigration control in the vertebrate body with special reference to chimerism.

Author information

1
London University, UK. tony.davies@blueyonder.co.uk

Abstract

The phenomenon of chimerism is reviewed against an understanding of adaptive immunity in vertebrates. It is shown that chimerism can be regarded as a ubiquitous condition and this suggests that monophylesis has played little part in evolution. It is suggested that the adaptive immune response has a special role in facilitating the development of chimerism and that the consensus view of adaptive immunity as a rejection mechanism should be revised.

KEYWORDS:

adaptive immunity; chimerism; communicable disease; evolution; innate immunity; symbiosis

PMID:
22690266
PMCID:
PMC3370924
[Indexed for MEDLINE]
Free PMC Article
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