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J Foot Ankle Surg. 2012 Sep-Oct;51(5):648-51. doi: 10.1053/j.jfas.2012.05.003. Epub 2012 Jun 9.

Massive heterotopic ossification around the ankle in a patient with macrodactyly of the foot: a case report.

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Department of Orthopaedic Surgery, Kagawa University Faculty of Medicine, Kagawa, Japan.


A 40-year-old man with macrodactyly of the left great toe presented with progressive enlargement of the ipsilateral ankle and increasing pain after minor trauma. Radiographs and computed tomographic scans of the foot and ankle revealed macrodactyly of the great toe and a large heterotopic ossified mass in the anteromedial aspect of the ankle. The large osseous lesion in the ankle was operatively excised. The lesion was easily excised en bloc after releasing the adhesion and histologically diagnosed as normal mature bone with osteoarthritic changes. Massive heterotopic ossification developing around the ankle in a patient with macrodactyly has not been previously reported. The current case was classified as hyperostotic macrodactyly. Operative treatment relieved the pain and improved the range of the motion of the ankle.

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