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Trop Med Int Health. 2012 Aug;17(8):978-88. doi: 10.1111/j.1365-3156.2012.03019.x. Epub 2012 Jun 12.

Prevalence and trend of HIV infection among voluntary blood donors in China since implementation of the Blood Donation Law: a systematic review and meta-analysis.

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1
Department of Social and Behavioral Health, School of Rural Public Health, Texas A&M Health Science Center, College Station, TX 77843, USA. yhong@srph.tamhsc.edu

Abstract

OBJECTIVE:

In 1998, the Blood Donation Law was enacted in China in response to the outbreak of HIV endemic in central rural China as a result of unhygienic and commercial blood collection. This study aims to provide a first comprehensive review of available data on the prevalence, trend and other epidemiological characteristics of HIV infection among voluntary blood donors since 1998.

METHODS:

Major English and Chinese databases were searched and a systematic review was constructed. Pooled infection rates by province and year were calculated using random-effect or fixed-effect models.

RESULTS:

A total of 87 studies met our inclusion criteria. A total of 2573 HIV-positive cases were identified among voluntary blood donors in the past 10 years; the pooled prevalence was 13.22/100,000, with a range of 0.74-125.97 per 100,000. Among the 24 provinces that reported yearly data, the prevalence of HIV increased from 5.62/100,000 to 28.90/100,000. The male-to-female ratio was 2.8; about 60% were below the age of 30 years.

CONCLUSIONS:

The prevalence of HIV in voluntary blood donors has risen steadily and fast. Efficient measures need to be taken urgently to prevent HIV test-seeking through blood donor programmes, to promote voluntary blood donation in low-risk groups and to enforce the Blood Donation Law strictly.

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