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Cell. 2012 Jun 8;149(6):1188-91. doi: 10.1016/j.cell.2012.05.022.

Getting RNA and protein in phase.

Author information

1
Princeton University, Department of Chemical and Biological Engineering, NJ 08544, USA.

Abstract

Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.

PMID:
22682242
DOI:
10.1016/j.cell.2012.05.022
[Indexed for MEDLINE]
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