The purpose of this study was to quantitatively evaluate the effects of different shades of light-polymerized resin cement on the color of two different thicknesses (0.5 mm and 0.7 mm) of three different ceramic materials (Esthetic, e.max, and ZirPress). A spectrophotometer (Color Eye 7000A - CIE (L*a*b*) was used to measure the color of specimens on the control substrate without cement, and then on (Translucent, White Opaque, B0.5, A1, and A3 of RelyX™ Veneer cement). The mean values of color difference (ΔE) were higher for Esthetic, followed by ZirPress, with the lowest values for e.max. The mean values of ΔE decreased when the thickness of ceramic increased from 0.5 mm to 0.7 mm. It was observed that the White Opaque had significantly increased ΔE values when compared with (TR, B0.5, A1, and A3), whereas no significant difference between B0.5 and TR, and between B0.5 and A3.