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Bioorg Med Chem Lett. 2012 Jul 1;22(13):4246-8. doi: 10.1016/j.bmcl.2012.05.021. Epub 2012 May 17.

Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta.

Author information

1
Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan.

Abstract

Makomotindoline (1) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline (1), its l-Glc isomer (2) and its aglycon (3) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth.

PMID:
22672800
DOI:
10.1016/j.bmcl.2012.05.021
[Indexed for MEDLINE]

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