Format

Send to

Choose Destination
Praxis (Bern 1994). 2012 Jun 6;101(12):775-9. doi: 10.1024/1661-8157/a000963.

[Effect of paracetamol (acetaminophen) on blood pressure in patients with coronary heart disease].

[Article in German]

Author information

1
Herzkreislaufzentrum Kardiologie, Universit├Ątsspital Z├╝rich. isabella.sudano@usz.ch

Abstract

Analgesic drugs, non-steroidal anti-inflammatory drugs and paracetamol (acetaminophen) in particular, belong to the most widely prescribed therapeutic agents. Beside their efficacy in pain relief, these drugs were recently linked to increased cardiovascular risk. Indeed, epidemiological and clinical studies showed that non-selective non-steroidal anti-inflammatory drugs, as well as selective cyclooxygenase-2 inhibitors both may increase blood pressure and cardiovascular events. However, the effect of paracetamol (acetaminophen) on blood pressure and cardiovascular health should not be neglected, too. Unfortunately, long-term randomized controlled trials appropriately powered to evaluate cardiovascular outcomes are lacking. This review summarizes the available data about the effect of paracetamol in particular, on blood pressure and other cardiovascular outcomes.

PMID:
22669780
DOI:
10.1024/1661-8157/a000963
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Atypon Icon for Zurich Open Access Repository and Archive
Loading ...
Support Center