Format

Send to

Choose Destination
See comment in PubMed Commons below
Thyroid. 2012 Jun;22(6):590-4. doi: 10.1089/thy.2011.0442.

Diagnostic yield of nondiagnostic thyroid nodules is not altered by timing of repeat biopsy.

Author information

1
Department of Surgery (Endocrine Surgery Unit), Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. clubitz@partners.org

Abstract

BACKGROUND:

Guidelines from the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference recommend a repeat fine-needle aspiration biopsy (FNAB) after 3 months for thyroid nodules with a nondiagnostic (ND) result. Our aims were to assess which factors influenced their clinical management and to determine if the timing of the repeat FNAB affects the diagnostic yield.

METHODS:

A retrospective institutional review of 298 patients from 1/2006 to 12/2007 with an ND FNAB was performed. The factors influencing the next step in management, including age, gender, history of radiation, presence of Hashimoto's thyroiditis, thyroid-stimulating hormone levels, and ultrasound characteristics, were evaluated. The effect of the time of the repeat FNABs on their diagnostic yield was assessed.

RESULTS:

Of the 298 patients in our cohort, 9% were referred directly for surgery, 76% had a repeat FNAB, and 15% were observed. Tumor size was the only independent variable correlated with treatment strategy after a ND FNAB. There was not a significant difference in diagnostic yields between repeat FNABs performed earlier than 3 months compared to those preformed later (p=0.58).

CONCLUSION:

The timing of repeat FNAB for an initial ND FNAB does not affect diagnostic yield of the repeat FNAB.

PMID:
22667452
PMCID:
PMC3733136
DOI:
10.1089/thy.2011.0442
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Mary Ann Liebert, Inc. Icon for PubMed Central
    Loading ...
    Support Center