Format

Send to

Choose Destination
Evid Based Complement Alternat Med. 2012;2012:404529. doi: 10.1155/2012/404529. Epub 2012 May 13.

The metabolism of baicalin in rat and the biological activities of the metabolites.

Author information

1
Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Liaoing 110016, China.

Abstract

Baicalin is one of the major bioactive constituents of Scutellariae Radix, but the biotransformation of it is poorly understood. In this paper, the metabolism of baicalin in rat was studied. Nine metabolites including one new compound were isolated and identified structurally. The plausible scheme for the biotransformation pathways of baicalin in the rats was deduced. And the main metabolites were evaluated for their antioxidation and anti-inflammation biological activities for the first time.

Supplemental Content

Full text links

Icon for Hindawi Publishing Corporation Icon for PubMed Central
Loading ...
Support Center