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Clin Microbiol Infect. 2012 Jul;18 Suppl 4:12-5. doi: 10.1111/j.1469-0691.2012.03863.x.

Human milk oligosaccharide consumption by intestinal microbiota.

Author information

1
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. marcobal@stanford.edu

Abstract

Human milk oligosaccharides (HMO) constitute the third most abundant class of molecules in breast milk. Since infants lack the enzymes required for milk glycan digestion, this group of carbohydrates passes undigested to the lower part of the intestinal tract, where they can be consumed by specific members of the infant gut microbiota. We review proposed mechanisms for the depletion and metabolism of HMO by two major bacterial genera within the infant intestinal microbiota, Bifidobacterium and Bacteroides.

PMID:
22647041
PMCID:
PMC3671919
DOI:
10.1111/j.1469-0691.2012.03863.x
[Indexed for MEDLINE]
Free PMC Article

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