Format

Send to

Choose Destination
See comment in PubMed Commons below
Nanomedicine. 2012 Sep;8 Suppl 1:S21-30. doi: 10.1016/j.nano.2012.05.011. Epub 2012 May 26.

Nanoparticle delivery for metastatic breast cancer.

Author information

1
Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA. Stephen.Grobmyer@surgery.ufl.edu

Abstract

Breast cancer represents a major ongoing public health problem as the most common non-cutaneous malignancy among U.S. women. While significant progress has been made in improving loco-regional treatments for breast cancer, relatively little progress has been made in diagnosing and treating patients with metastatic breast cancer. At present there are limited curative options for patients with breast cancer metastatic beyond regional nodes. Emerging nanotechnologies promise new approaches to early detection and treatment of metastatic breast cancer. Fulfilling the promise of nanotechnologies for patients with metastatic breast cancer will require delivery of nanomaterials to sites of metastatic disease. Future translational approaches will rely on an ever increasing understanding of the biology of breast cancer subtypes and their metastases. These important concepts will be highlighted and elucidated in this manuscript.

PMID:
22640908
DOI:
10.1016/j.nano.2012.05.011
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center