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J Pharmacol Pharmacother. 2012 Apr;3(2):196-9. doi: 10.4103/0976-500X.95532.

Ethionamide-induced gynecomastia.

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Department of Respiratory Medicine, J. L. N. Medical College, Ajmer, India.


Gynecomastia is very rare during antituberculosis chemotherapy. We describe a 38-year-old male patient who developed a painful gynecomastia following second-line drug therapy for multidrug-resistant pulmonary tuberculosis. Gynecomastia disappeared after stopping the ethionamide. A published literature on antituberculosis-induced gynecomastia is also briefly discussed.


Antituberculosis therapy; drug-induced gynecomastia; ethionamide

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