Format

Send to

Choose Destination
See comment in PubMed Commons below
Chimerism. 2012 Apr-Jun;3(2):45-7. doi: 10.4161/chim.20739. Epub 2012 Apr 1.

Fetal microchimerism in skin wound healing.

Author information

1
Université Pierre et Marie Curie; Paris, France. dany.nassar@inserm.fr

Abstract

Skin wound healing is a complex regenerative process involving various cell types. We recently investigated whether fetal microchimeric cells (FMCs) acquired during gestation contribute to maternal wound healing and used fetal microchimerism to investigate the recruitment of distant endothelial progenitor cells in skin wounds. Our study showed that fetal progenitor cells are recruited into maternal wounds and participate in inflammation and angiogenesis. These fetal cells might have beneficial effects in situations of maternal defective healing, and might also modify the adult maternal wound environment toward a scarless fetal-like wound healing.

PMID:
22627845
PMCID:
PMC3442813
DOI:
10.4161/chim.20739
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis Icon for PubMed Central
    Loading ...
    Support Center