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Curr Biol. 2012 May 22;22(10):R411-3. doi: 10.1016/j.cub.2012.03.055.

Cortical circuits: layer 6 is a gain changer.

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1
The National Institute for Medical Research, The Ridgeway, London, UK.

Abstract

Stimulation of excitatory cells in layer six of mouse visual cortex results in net inhibition of the spiking of neurons in upper cortical layers; this ascending intra-cortical drive provides a mechanism for gain modulation of sensory-evoked responses.

PMID:
22625861
DOI:
10.1016/j.cub.2012.03.055
[Indexed for MEDLINE]
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