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Biomarkers. 2012 Sep;17(6):507-12. doi: 10.3109/1354750X.2012.690103. Epub 2012 May 23.

Advanced oxidation protein products as prognostic biomarkers for recovery from acute kidney injury after coronary artery bypass grafting.

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1
Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, China.

Abstract

Recovery from acute kidney injury (AKI) is related to long-term prognosis. This study, involving 56 patients with AKI and 56 controls from a prospective cohort undergoing coronary artery bypass grafting (CABG), investigated the prognostic performance of serum levels of advanced oxidation protein products (AOPPs) for predicting non-recovered AKI and non-completely recovered AKI. AOPP levels increased significantly 7 days after surgery in patients with non-recovered or non-completely recovered AKI. Increased AOPP levels were associated with both types of poor recovery from AKI. Results from receiver-operating characteristic (ROC) curves demonstrated that AOPP levels had good prognostic value for predicting non-recovered and non-completely recovered AKI.

PMID:
22616978
PMCID:
PMC3469238
DOI:
10.3109/1354750X.2012.690103
[Indexed for MEDLINE]
Free PMC Article
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