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ACS Nano. 2012 Jun 26;6(6):5304-8. doi: 10.1021/nn301125y. Epub 2012 May 24.

Real-time stochastic detection of multiple neurotransmitters with a protein nanopore.

Author information

1
Department of Chemistry, University of Oxford, Oxford, OX1 3TA, United Kingdom.

Abstract

The detection of several different neurotransmitters with the same sensor in real-time would be a powerful asset to the field of neurochemistry. We have developed a detector for a broad range of neurotransmitters including amino acids, catecholamines, and nucleotides, which relies on the reversible binding of the analytes to a copper(II) complex within an engineered protein nanopore.

PMID:
22616662
DOI:
10.1021/nn301125y
[Indexed for MEDLINE]

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