Format

Send to

Choose Destination
J Pediatr Gastroenterol Nutr. 2012 Nov;55(5):612-4. doi: 10.1097/MPG.0b013e31825eff61.

Pancreatic insufficiency is not a prevalent problem in Alagille syndrome.

Author information

1
Hospital for Sick Children, Toronto, Canada. binita.kamath@sickkids.ca

Abstract

Alagille syndrome (ALGS) is an inherited multisystem disorder in which pancreatic insufficiency (PI) has been regarded a minor but important clinical manifestation. As part of a multicenter prospective study, 42 patients with ALGS underwent fecal elastase (FE) measurement to screen for exocrine PI. FE measurements were normal (>200  μg/g) in 40 (95%) and indeterminate (100-200  μg/g) in 2 (5%). As FE is the most reliable screen for PI, these data suggest that PI is not a prevalent problem in ALGS.

PMID:
22614108
PMCID:
PMC3666161
DOI:
10.1097/MPG.0b013e31825eff61
[Indexed for MEDLINE]
Free PMC Article

Publication type, MeSH terms, Substances, Grant support

Publication type

MeSH terms

Substances

Grant support

Supplemental Content

Full text links

Icon for Wolters Kluwer Icon for PubMed Central
Loading ...
Support Center