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Dev Cell. 2012 May 15;22(5):911-2. doi: 10.1016/j.devcel.2012.05.003.

In search of Turing in vivo: understanding Nodal and Lefty behavior.

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1
Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan. hamada@fbs.osaka-u.ac.jp

Abstract

The Turing reaction-diffusion model proposes that short-range activators and long-range inhibitors can generate complex patterns. In a Science study, Müller et al. (2012) assess behavioral determinants of Nodal and Lefty, TGFβ-related molecules that constitute an activator/inhibitor system, and provide evidence that the factors indeed form a reaction-diffusion system.

PMID:
22595667
DOI:
10.1016/j.devcel.2012.05.003
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