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Funct Integr Genomics. 2012 Aug;12(3):489-500. doi: 10.1007/s10142-012-0283-2. Epub 2012 May 17.

New cis-regulatory elements in the Rht-D1b locus region of wheat.

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College of Biology Sciences, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, People's Republic of China.


Fifteen gene-containing BACs with accumulated length of 1.82-Mb from the Rht-D1b locus region were sequenced and compared in detail with the orthologous regions of rice, sorghum, and maize. Our results show that Rht-D1b represents a conserved genomic region as implied by high gene sequence identity, good maintenance of gene colinearity, and the presence of multiple conserved noncoding sequences (CNSs) that are shared by other grass species. Eight cis-regulatory elements in these CNSs around grass DELLA genes were detected.

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