Format

Send to

Choose Destination
See comment in PubMed Commons below
J Neurosci Methods. 1990 Sep;34(1-3):35-46.

Microdialysis measurement of in vivo neuropeptide release.

Author information

1
A.F.R.C. Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, U.K.

Abstract

The application of the microdialysis sampling technique for in vivo measurement of neuropeptide release is discussed. In vitro recoveries of different microdialysis membranes are described for a variety of neuropeptides (ranging from 400 to 4500 MW) as well as their dynamic potential for measuring external concentration changes. In vivo experiments illustrating the use of the technique for measuring release of oxytocin and met-enkephalin from the brain of the conscious sheep, and vasopressin in the blood of the anaesthetised rat are described.

PMID:
2259245
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center