Format

Send to

Choose Destination
Proteomics. 2012 May;12(9):1463-71. doi: 10.1002/pmic.201100240.

Proteomic analysis of the microenvironment of developing oocytes.

Author information

1
Department of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Abstract

We utilized a setup based on extensive pre-fractionation of proteolytic peptides and nanoflow reversed-phase LC-MS/MS to identify the (sub)proteome of human follicular fluid (FF). In this in-depth screen, 246 specific proteins were identified, the majority of which are involved in coagulation- and immune-response pathways. Our aim is to define a set of FF protein markers, which could predict oocyte quality.

PMID:
22589193
DOI:
10.1002/pmic.201100240
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center