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Otolaryngol Clin North Am. 2012 Jun;45(3):671-94, viii-ix. doi: 10.1016/j.otc.2012.03.006.

Recurrent respiratory papillomatosis.

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1
Department of Otolaryngology, University of Texas Medical Branch, 7.104 John Sealy Annex, 301 University Boulevard, Galveston, TX 77555-0521, USA.

Abstract

Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.

PMID:
22588043
PMCID:
PMC3682415
DOI:
10.1016/j.otc.2012.03.006
[Indexed for MEDLINE]
Free PMC Article
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