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Res Vet Sci. 2012 Dec;93(3):1307-8. doi: 10.1016/j.rvsc.2012.04.011. Epub 2012 May 14.

The effects of sage extract feed supplementation on biochemical parameters, weight of internal organs and Salmonella counts in chickens.

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University of Veterinary Medicine and Pharmacy, Department of Pathological Anatomy and Pathological Physiology, Komenskeho 73, 041 81 Kosice, Slovakia.


We investigated the effects of dietary addition of sage extract on the biochemical parameters, weight of some body organs and changes in the counts of Salmonella Enteritidis PT4 (SE) in experimentally infected chickens. The following diets were used: basal diet, basal diet with addition of an extract of Salvia officinalis L. (S), basal diet and SE, and basal diet and S and SE (SSE). Compared to the SE group, sage extract in the SSE group decreased activities of ALP and ALT and concentrations of glucose and bilirubin on the 4th day post inoculation (p.i.). However, on the 18th day p.i., lower levels of bilirubin and ALT activity only were detected. Addition of sage extract to the diets decreased the counts of Salmonella in the liver, spleen and caecum at both sampling times, along with lower production of mucus in the chickens' intestines. Our results suggest that the addition of sage extract to the diet could be effective in protecting SE-infected chickens.

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