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Cancer Discov. 2011 Dec;1(7):557-9. doi: 10.1158/2159-8290.CD-11-0271. Epub 2011 Nov 9.

A combined epigenetic therapy equals the efficacy of conventional chemotherapy in refractory advanced non-small cell lung cancer.

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1
Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.

Abstract

A new study by Juergens and colleagues provides the first successful example of a combined epigenetic therapy capable of achieving results similar to those of conventional chemotherapy in refractory metastatic non-small cell lung cancer. Furthermore, the authors describe interesting blood-based DNA methylation biomarkers that may be useful in predicting clinical response.

PMID:
22586680
DOI:
10.1158/2159-8290.CD-11-0271
[Indexed for MEDLINE]
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