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Muscle Nerve. 2012 Jun;45(6):815-9. doi: 10.1002/mus.23271.

Geographical distribution of a seropositive myasthenia gravis population.

Author information

1
Department of Clinical Medicine, University of Bergen, Bergen, Norway. ahe002@student.uib.no

Abstract

INTRODUCTION:

To assess age- and sex-specific myasthenia gravis (MG) occurrence and incidence in the different geographical regions in Norway and thereby to identify factors that may contribute to the development of MG.

METHODS:

Multiple Poisson regression analysis was used to assess variation in incidence dependent on year, gender and onset age in five geographically defined health regions.

RESULTS:

The study population comprised 419 individuals with first time seropositive tests from 1995 to 2007. Annual MG incidence ranged from < 1 to 14 per million, with an average of 7.04 per million for all five health regions combined.

CONCLUSIONS:

This is the first nation-wide epidemiological study of seropositive MG that elucidates the geographical differences within a country. The incidence of seropositive MG did not vary significantly between the regions. Mid-Norway tended to have a higher incidence, and North tended to have a lower incidence.

PMID:
22581533
DOI:
10.1002/mus.23271
[Indexed for MEDLINE]
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