Format

Send to

Choose Destination
See comment in PubMed Commons below
Dalton Trans. 2012 Jun 21;41(23):6906-9. doi: 10.1039/c2dt30357d. Epub 2012 May 11.

Zeolitic Imidazolate framework-8 as efficient pH-sensitive drug delivery vehicle.

Author information

1
Institute of Functional Materials Chemistry, Key Laboratory of Polyoxometalate Science of Ministry of Education Department of Chemistry, Northeast Normal University, Changchun, 130024, China.

Abstract

Zeolitic Imidazolate Framework-8 (ZIF-8), for the first time for ZIFs, exhibits a remarkable capacity for the anticancer drug 5-fluorouracil (5-FU), around 660 mg of 5-FU/g of ZIF-8, and presents a pH-triggered controlled drug release property. These prove ZIF-8 to be a valuable candidate for delivery of anticancer agents and reveal its potential applications in the treatment of cancer.

PMID:
22580798
DOI:
10.1039/c2dt30357d
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry
    Loading ...
    Support Center