Format

Send to

Choose Destination
Br J Pharmacol. 2012 Oct;167(3):483-92. doi: 10.1111/j.1476-5381.2012.02031.x.

Retinoids: novel immunomodulators and tumour-suppressive agents?

Author information

1
Department of Biomedical Sciences and Human Oncology, University of Bari 'Aldo Moro', Bari, Italy.

Abstract

Retinoids play important roles in the transcriptional activity of normal, degenerative and tumour cells. Retinoid analogues may be promising therapeutic agents for the treatment of immune disorders as different as type I diabetes and systemic lupus erythematosus. In addition, the use of retinoids in cancer treatment has progressed significantly in the last two decades; thus, numerous retinoid compounds have been synthesized and tested. In this paper, the actual or potential use of retinoids as immunomodulators or tumour-suppressive agents is discussed.

PMID:
22577845
PMCID:
PMC3449254
DOI:
10.1111/j.1476-5381.2012.02031.x
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center