Format

Send to

Choose Destination
See comment in PubMed Commons below
Cancer Discov. 2012 Apr;2(4):301-3. doi: 10.1158/2159-8290.CD-12-0067.

A spotlight from prostate cancer.

Author information

  • 1Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA. hherschman@mednet.ucla.edu

Abstract

Serum prostate-specific antigen (PSA) levels are used to monitor the development of prostate cancer, recurrence after surgery, and response to subsequent therapy. However, the clinical implications often are difficult to interpret. Ulmert and colleagues report use of a positron-emitting labeled monoclonal antibody directed to a unique PSA epitope to noninvasively image PSA-positive prostate cancer xenografts and to measure both androgen-stimulated PSA expression and androgen therapy-responsive PSA decreases.

PMID:
22576205
DOI:
10.1158/2159-8290.CD-12-0067
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center