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Molecules. 2012 May 9;17(5):5467-96. doi: 10.3390/molecules17055467.

Solid-phase parallel synthesis of drug-like artificial 2H-benzopyran libraries.

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1
Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Buk-gu, Daegu, Korea. tlee@knu.ac.kr

Abstract

This review covers the construction of drug-like 2H-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran derivatives and additional ring-fused benzopyrans such as benzopyranoisoxazoles, benzopyranopyrazoles, six-membered ring-fused benzopyrans, and polycyclic benzopyrans are highlighted.

PMID:
22572931
DOI:
10.3390/molecules17055467
[Indexed for MEDLINE]
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