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Oman Med J. 2008 Jan;23(1):34-9.

Epidemiological characteristics of corneal ulcers in South sharqiya region.

Abstract

OBJECTIVES:

To understand the epidemiology, predisposing factors, etiology and the outcome of management of corneal ulcers in South Sharqiya Region of Oman.

METHODS:

188 patients who presented to us in eye Ophthalmology Department of Sur regional hospital with corneal ulcers were analyzed retrospectively. The historical aspects including the systemic and local predisposing factors, clinical picture of the ulcer which was noted on slit lamp at the time of presentation, results of culture for which material was taken by scraping of the ulcer, and its sensitivity pattern, type of management, and its outcome, were noted and the results were interpreted.

RESULTS:

60.83% were males above the age of 60 years. Severe ulcers were seen in 36.17% of cases. 43.18% of cases showed positive culture of which 88.2% were bacteria and rest were fungal isolates. Of the bacteria 53.84% were pseudomonas, and 20% staphylococcus. 83.5% were put on fortified gentamycin and 68.61% were on cefuroxime in the initial dual therapy. 37.23% were on ciprofloxacin one time or another during the course of the ulcer. 69.14% of cases recovered fully and 9.57% improved. 54.25% needed hospitalization for less than 1 week and 34% for less than 2 weeks. 58.76% of cases recovered in less than 3 weeks. As local predisposing factors 45 cases (24%) were post surgery, and 29 cases (15.4%) were having CDK (climatic droplet keratopathy). Diabetes was seen in 8.5% of cases.

CONCLUSION:

Corneal ulcer was seen predominantly in males above the age of 60 years, pseudomonas being the main etiological organism. Dual therapy was the commonest empirical therapy. No major systemic risk factor was identified. Post surgical and CDK were the predominant local risk factors.

KEYWORDS:

corneal ulcer; dual therapy; pseudomonas

PMID:
22567208
PMCID:
PMC3338994
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