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Transplant Proc. 2012 May;44(4):913-4. doi: 10.1016/j.transproceed.2012.01.085.

Heart retransplantation for pediatric primary allograft failure.

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1
Department of Cardiovascular Surgery, National Taiwan University Hospital, Taipei, Taiwan.

Abstract

PURPOSE:

Heart transplantation is indicated for children with end-stage heart failure or complex inoperable congenital defects. When the transplanted heart fails, retransplantation is suggested and herein we have presented the prognosis of these pediatric cases.

MATERIALS AND METHODS:

From March 1987 to March 2011, we performed 404 heart transplantations including 45 pediatric patients, 6 (13.3%) of whom experienced graft failure requiring retransplantation. Only four of the six patients (66.7%) had a chance for retransplantation.

RESULTS:

Six of 45 pediatric heart transplant patients (13.3%) experienced graft failure requiring retransplantation. Four of them (66.7%) underwent retransplantation. Only one of the four died due to severe postoperative sepsis with acute respiratory distress. The other three patients recovered well and remain alive with no neurological sequelae; all are in New York Heart Association functional classification I at present.

CONCLUSION:

Pediatric post-heart graft failure require expectations retransplantation, which shows a good prognosis.

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