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Int J Pharm. 2012 Jul 15;431(1-2):241-4. doi: 10.1016/j.ijpharm.2012.04.015. Epub 2012 Apr 24.

Corrosion inhibitors from expired drugs.

Author information

1
University Politehnica of Timişoara, 300006 Piaţa Victoriei 2, Timişoara, Romania. nicolae.vaszilcsin@chim.upt.ro

Abstract

This paper presents a method of expired or unused drugs valorization as corrosion inhibitors for metals in various media. Cyclic voltammograms were drawn on platinum in order to assess the stability of pharmaceutically active substances from drugs at the metal-corrosive environment interface. Tafel slope method was used to determine corrosion rates of steel in the absence and presence of inhibitors. Expired Carbamazepine and Paracetamol tablets were used to obtain corrosion inhibitors. For the former, the corrosion inhibition of carbon steel in 0.1 mol L(-1) sulfuric acid solution was about 90%, whereas for the latter, the corrosion inhibition efficiency of the same material in the 0.25 mol L(-1) acetic acid-0.25 mol L(-1) sodium acetate buffer solution was about 85%.

PMID:
22561212
DOI:
10.1016/j.ijpharm.2012.04.015
[Indexed for MEDLINE]

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