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J Clin Pathol. 2012 Sep;65(9):819-22. doi: 10.1136/jclinpath-2012-200808. Epub 2012 May 3.

Complex adnexal tumours of the skin: a report of three cases and review of literature.

Author information

1
Department of Dermatology, University of Southern California-Keck School of Medicine, Los Angeles, California, USA.

Abstract

AIMS:

Complex or composite adnexal tumours of the skin (CATS) are unusual neoplasms composed of two or more histopathologically distinct subtypes of appendageal neoplasms coexisting in a single cutaneous lesion. The authors report three examples of CATS, review literature and discuss their probable histogenesis.

METHODS AND RESULTS:

Of the three tumours described, one tumour showed a mixture of a proliferating pilar tumour and syringocystadenoma papilliferum, the second lesion was composed of a proliferating pilar tumour and tubulopapillary hidradenoma and the third tumour exhibited a syringocystadenoma papilliferum and tubulopapillary hidradenoma in combination.

CONCLUSIONS:

CATS are rare tumours. The authors reported three unique cases in addition to the 10 other reported cases. These three cases further strengthen the hypothesis of a 'folliculosebaceous apocrine' unit as the most likely point of origin of CATS.

PMID:
22554961
DOI:
10.1136/jclinpath-2012-200808
[Indexed for MEDLINE]

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