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Psychiatry Res. 2012 Dec 30;200(2-3):1011-3. doi: 10.1016/j.psychres.2012.04.007. Epub 2012 May 1.

Association study of copy number variants with brain volume in schizophrenia patients and healthy controls.

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1
Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Huispostnummer A00.241, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands. aterwiss@umcutrecht.nl

Abstract

Schizophrenia patients have more copy number variations (CNVs) than healthy controls, and reduced brain volumes. Although this could suggest a causal relationship, we found no association between global CNV burden and three brain volume measures (on a MRI scan) in a sample of 173 schizophrenia patients and 176 healthy controls.

PMID:
22551941
DOI:
10.1016/j.psychres.2012.04.007
[Indexed for MEDLINE]
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