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Endocr Pract. 2012 Sep-Oct;18(5):e127-9. doi: 10.4158/EP11373.CR.

Apathetic thyrotoxicosis secondary to atypical subacute thyroiditis.

Author information

1
Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA. Alessia.Carluccio@mountsinai.org

Abstract

OBJECTIVE:

To report a case of apathetic thyrotoxicosis with an etiology of subacute thyroiditis.

METHODS:

We describe the patient's clinical findings, laboratory findings, and clinical course.

RESULTS:

An 85-year-old woman with no history of thyroid disease presented with severe obtundation and altered mental status. Laboratory testing documented elevated free thyroxine and free triiodothyronine concentrations and a suppressed thyrotropin concentration. Thyroid antibodies were absent. A radioactive iodine study revealed severely diminished uptake, suggestive of thyroiditis. After a short course of steroids, the patient's mental status returned to baseline. Follow-up laboratory testing showed normalizing thyroid function.

CONCLUSION:

Even in the absence of a history of thyroid disease, we recommend considering thyroid dysfunction in the differential diagnosis of patients who present with altered mental status, particularly in the elderly population.

PMID:
22548945
DOI:
10.4158/EP11373.CR
[Indexed for MEDLINE]

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