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Gastroenterol Hepatol. 2012 Oct;35(8):585-93. doi: 10.1016/j.gastrohep.2012.02.005. Epub 2012 Apr 26.

[Influence of non-alcoholic fatty liver disease on cardiovascular disease].

[Article in Spanish]

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Unidad de Gestión Clínica de Enfermedades Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, España.


Non-alcoholic fatty liver disease encompasses a spectrum ranging from simple steatosis to steatohepatitis without excess alcohol intake and is considered to be the hepatic manifestation of metabolic syndrome. Recent studies indicate that non-alcoholic fatty liver disease is closely related to cardiovascular disease, especially to thickening of the intima-media layer of the carotid artery, as the morphostructural manifestation of the presence of subclinical atheromatosis. Therefore, the correct management of non-alcoholic fatty liver disease would allow the natural history of both the liver disease and the atherosclerosis to be modified.

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