Format

Send to

Choose Destination
See comment in PubMed Commons below
Nutrition. 2012 Jul;28(7-8):e27-32. doi: 10.1016/j.nut.2012.01.007. Epub 2012 Apr 26.

Effect of suboptimal breast-feeding on occurrence of autism: a case-control study.

Author information

1
Department of Family Medicine and Public Health, Sultan Qaboos University, Al-Khoudh, Sultanate of Oman. ymfarsi@squ.edu.om

Abstract

OBJECTIVE:

To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs).

METHODS:

A case-control study was conducted in 102 ASD cases and 102 matched healthy controls.

RESULTS:

Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001).

CONCLUSION:

The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices.

PMID:
22541054
DOI:
10.1016/j.nut.2012.01.007
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center