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Ugeskr Laeger. 2012 Apr 23;174(17):1149-51.

[Multiple self-healing squamous epithelioma is an inherited self-healing skin cancer condition].

[Article in Danish]

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Hudafdeling I og Allergicentret, Odense Universitetshospital, Denmark.


Multiple self-healing squamous epithelioma - Ferguson-Smith disease (MSSE) is an autosomal dominant inherited disease with multiple, recurrent, histologically malignant tumours that undergo spontaneous regression. The gene for MSSE has recently been identified as the transforming growth factor-beta receptor 1 (TGFBR1). Although rare, MSSE constitutes an important model of tumour-biology research. The discovery of the genetic background for MSSE paves the way for further elucidating the mechanisms involved in this peculiar self-healing cancer syndrome.

[Indexed for MEDLINE]

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