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Br J Haematol. 2012 Jul;158(1):62-78. doi: 10.1111/j.1365-2141.2012.09131.x. Epub 2012 Apr 26.

Organ-specific management and supportive care in chronic graft-versus-host disease.

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Section of Haemato-oncology, The Royal Marsden NHS Foundation Trust, London, UK.


A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology and the British Society for Bone Marrow Transplantation has reviewed the available literature and made recommendations for the supportive care and management of organ-specific complications of chronic graft-versus-host disease (cGvHD). This guideline includes recommendations for the specific therapy of skin, oral, liver, gut, lung, ocular and genital manifestations of cGvHD and for the supportive care of these patients, including vaccinations and prophylaxis against infection. The goal of treatment should be effective control of GvHD while minimizing the risk of toxicity and relapse.

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