Format

Send to

Choose Destination
See comment in PubMed Commons below
Oxid Med Cell Longev. 2012;2012:314758. doi: 10.1155/2012/314758. Epub 2012 Mar 11.

Mate tea prevents oxidative stress in the blood and hippocampus of rats with acute or chronic ethanol administration.

Author information

1
Centro de Ciências Exatas e Naturais, Departamento de Ciências Naturais, Universidade Regional de Blumenau, Blumenau, SC, Brazil. deboradelwing@furb.br

Abstract

OBJECTIVE:

The aim of this study was to evaluate the influence of acute and chronic intake of mate tea on the effects elicited by acute and chronic administration of ethanol.

METHODS:

Oxidative stress was evaluated by measuring thiobarbituric acid-reactive substances (TBARS), as well as the activities of the antioxidant enzymes, catalase (CAT), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) in the hippocampus and blood of rats. Male Wistar rats were randomly assigned to four groups, for both acute and chronic treatment: (1) control group, (2) treated group, (3) intoxicated group, (4) and intoxicated group treated with mate tea.

RESULTS:

Both ethanol administrations significantly increased TBARS in plasma and hippocampus of rats and altered antioxidant enzyme activities, changes which were reverted by mate tea administration.

CONCLUSIONS:

Data indicate that acute and chronic ethanol administration induced oxidative stress in hippocampus and blood and that mate tea treatment was able to prevent this situation.

PMID:
22530075
PMCID:
PMC3316984
DOI:
10.1155/2012/314758
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Hindawi Publishing Corporation Icon for PubMed Central
    Loading ...
    Support Center