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Adv Mater. 2012 May 22;24(20):2703-9. doi: 10.1002/adma.201104072. Epub 2012 Apr 23.

Hierarchical formation of supramolecular transient networks in water: a modular injectable delivery system.

Author information

1
Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands.

Abstract

A modular one-component supramolecular transient network in water, based on poly(ethylene glycol) and end-capped with four-fold hydrogen bonding units, is reported. Due to its nonlinear structural formation, this system allows active proteins to be added to the hydrogel during formation. Once implanted in vivo it releases the protein by erosion of both the protein and polymer via dissolution.

PMID:
22528786
DOI:
10.1002/adma.201104072
[Indexed for MEDLINE]

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